When it does not arrive or does not match.
If an order does not arrive, arrives short, or arrives unusable, open a dispute rather than confirming. Osiris moderators are known for responding fast, which matters most exactly when you have a case open.
Open when a vendor has gone quiet past a reasonable window, when the order is well past its shipping time, or when what arrived does not match. Not before.
Your account, your evidence, the full message thread, and the vendor's history. Bring clear photos and a calm factual account. Keep the language factual, answer questions quickly, and do not finalise early hoping a vendor will reward you by shipping.